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2-[(1H-Benzimidazol-2-Ylmethyl)Sulfanyl]-3-(4-Chlorophenyl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One CAS NO 354795-49-6


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CAS No.:354795-49-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[(1H-Benzimidazol-2-Ylmethyl)Sulfanyl]-3-(4-Chlorophenyl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One is a sophisticated heterocyclic organic compound that serves as a key advanced intermediate in modern pharmaceutical research and development. Its complex molecular architecture, featuring fused benzimidazole, thienopyrimidine, and cyclopentane rings, makes it a highly valuable scaffold for designing novel bioactive molecules. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
  • Biochemical Research: Used as a reference standard or a probe compound in enzymatic and cellular assays to study specific biological pathways.
  • Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
  • Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.
  • Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Item Details
Product Name 2-[(1H-Benzimidazol-2-Ylmethyl)Sulfanyl]-3-(4-Chlorophenyl)-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One
CAS No. 354795-49-6
Molecular Formula C23H19ClN4OS2
Molecular Weight 474.99 g/mol
Synonyms 3-(4-Chlorophenyl)-2-[(1H-benzimidazol-2-ylmethyl)thio]-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one; 2-[(1H-Benzimidazol-2-ylmethyl)thio]-3-(4-chlorophenyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one; 354795-49-6; Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one derivative; Benzimidazole-thienopyrimidine conjugate
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Quality Control

Our production of this high-purity advanced intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation, ensuring it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data and spectral information are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance Off-white to light yellow solid
Identification (HPLC) Retention time corresponds to reference standard
Identification (MS) Consistent with molecular structure
Purity (HPLC) ≥ 95.0% (Area Percent)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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