Description

4-Bromoquinazoline is a versatile and high-value brominated heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive bromine atom, which facilitates efficient cross-coupling reactions and further functionalization to create complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel quinazoline-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with quinazoline cores.
• Material Science: Used in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive compounds.
• Chemical Synthesis: Serves as a versatile substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Academic & R&D: Fundamental reagent for methodological development and exploring new reaction pathways in heterocyclic chemistry.
• Ligand Synthesis: Intermediate for preparing sophisticated nitrogen-donor ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromoquinazoline
CAS No.	354574-59-7
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	4-Bromoquinazoline; Quinazoline, 4-bromo-; 4-Bromo-quinazoline; 354574-59-7; 4-Brom-chinazolin (German); 4-ブロモキナゾリン (Japanese); Bromure de 4-quinazolinyle
EINECS	Contact for details

Quality Control

Every batch of our 4-Bromoquinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.