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Ac-Arg-Cys-Met-5-Aminopentanoyl-Arg-Val-Tyr-5-Aminopentanoyl-Cys-Nh2, (Disulfide Bond) Trifluoroacetate CAS NO 353487-64-6


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CAS No.:353487-64-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ac-Arg-Cys-Met-5-Aminopentanoyl-Arg-Val-Tyr-5-Aminopentanoyl-Cys-Nh2, (Disulfide Bond) Trifluoroacetate is a synthetic, chemically modified peptide featuring a critical intramolecular disulfide bridge. This compound is of significant value in advanced research and development, particularly for studying peptide structure-function relationships, stability, and receptor interactions. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on peptide-based therapeutics, diagnostic tools, and biochemical probes.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and optimization of novel peptide-based drugs targeting specific biological pathways.
  • Biochemical & Biophysical Studies: Used to investigate the role of disulfide bonds in peptide folding, conformational stability, and biological activity under various conditions.
  • Receptor-Ligand Interaction Analysis: Employed in binding assays (e.g., SPR, ELISA) to characterize affinity and specificity for target receptors or enzymes.
  • Proteomics & Signal Transduction Research: Acts as a tool compound to modulate or probe specific cellular signaling cascades in experimental models.
  • Diagnostic Reagent Development: Potential use as a component in the development of sensitive and specific diagnostic assays or imaging agents.
  • Peptide Library Synthesis: Can be utilized as a building block or template for constructing focused libraries to screen for desired biological properties.

Basic Information

Product Name Ac-Arg-Cys-Met-5-Aminopentanoyl-Arg-Val-Tyr-5-Aminopentanoyl-Cys-Nh2, (Disulfide Bond) Trifluoroacetate
CAS No. 353487-64-6
Molecular Formula C52H86N16O13S3 • xC2HF3O2
Molecular Weight ~1271.5 g/mol (Free base, disulfide form)
Synonyms Ac-Arg-Cys-Met-Ahx-Arg-Val-Tyr-Ahx-Cys-NH2 (Disulfide); Cyclic(Ac-RCMAhxRVYAhxC-NH2); Ac-RCM(Ahx)RVY(Ahx)C-NH2 (Disulfide Bridge); Ac-Arg-Cys-Met-6-Aminohexanoyl-Arg-Val-Tyr-6-Aminohexanoyl-Cys-amide (Disulfide); Ahx = 5-Aminopentanoyl / 6-Aminohexanoic acid linker; Custom Peptide 353487-64-6; TFA salt of disulfide-linked peptide
EINECS Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC for purity, MS (Mass Spectrometry) for identity confirmation, and amino acid analysis. We support research and development with materials suitable for non-GMP applications, with purity levels typically exceeding 95%.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC & MS) Retention time and mass consistent with reference
Purity (HPLC) ≥ 95%
Amino Acid Composition Within ±10% of theoretical values
Net Peptide Content ≥ 70%
Water Content (KF) ≤ 8.0%
Single Impurity (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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