Description

6-Chloro-5-[(4,5-Dihydro-1H-Imidazol-2-Yl)Amino]-2-Methyl-4(1H)-Pyrimidinone is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those with imidazoline and pyrimidinone pharmacophores.
• Biochemical Research: Used as a reference standard or reagent in enzymatic and receptor-binding studies to investigate biological mechanisms.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new therapeutics for cardiovascular, metabolic, or neurological disorders.
• Chemical Synthesis: Employed in organic synthesis to construct more complex nitrogen-containing heterocyclic compounds.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents due to its bioactive structure.

Basic Information

Item	Details
Product Name	6-Chloro-5-[(4,5-Dihydro-1H-Imidazol-2-Yl)Amino]-2-Methyl-4(1H)-Pyrimidinone
CAS No.	352457-33-1
Molecular Formula	C8H10ClN5O
Molecular Weight	227.65 g/mol
Synonyms	6-Chloro-2-methyl-5-[(4,5-dihydro-1H-imidazol-2-yl)amino]pyrimidin-4(1H)-one; 2-Methyl-6-chloro-5-(2-imidazolin-2-ylamino)-4(1H)-pyrimidinone; 5-[(4,5-Dihydro-1H-imidazol-2-yl)amino]-6-chloro-2-methyl-4(1H)-pyrimidinone; 352457-33-1; 6-Chloro-5-(4,5-dihydro-1H-imidazol-2-ylamino)-2-methyl-1,4-dihydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-[(4,5-Dihydro-1H-Imidazol-2-Yl)Amino]-2-Methyl-4(1H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.