Description

Fmoc-L-2,4-Dichlorophe CAS NO 352351-62-3 is a protected amino acid derivative, specifically an Fmoc-protected unnatural amino acid featuring a dichlorophenyl side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise incorporation of halogenated aromatic residues to modulate peptide properties. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced materials science who require high-purity, specialized amino acids for creating novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated synthesis of peptides containing halogenated aromatic amino acids.
• Pharmaceutical Research & Development: Used to create peptide-based drug candidates, where the dichlorophenyl group can enhance binding affinity, metabolic stability, and lipophilicity.
• Agrochemical Peptide Mimetics: Employed in the design of novel pesticides and herbicides that mimic natural peptide hormones in pests or plants.
• Chemical Biology Probes: Incorporation into peptides used as probes to study protein-protein interactions and enzyme mechanisms.
• Material Science: Serves as a monomer for constructing peptidomimetic polymers and advanced functional materials with specific electronic or structural properties.

Basic Information

Product Name	Fmoc-L-2,4-Dichlorophe
CAS No.	352351-62-3
Molecular Formula	C24H19Cl2NO4
Molecular Weight	456.32 g/mol
Synonyms	Fmoc-2,4-dichloro-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-dichloro-L-phenylalanine; Fmoc-2,4-Dichloro-L-Phe-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-(2,4-dichlorophenyl)propanoic acid; Fmoc-L-(2,4-DiCl)Phe; N-Fmoc-2,4-dichloro-L-phenylalanine
EINECS	Contact for details

Quality Control

Every batch of Fmoc-L-2,4-Dichlorophe is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and chiral integrity, to ensure compliance with industry standards for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.