Description

1,2-Benzenediol,4-(2,2,2-Trifluoro-1-Hydroxyethyl)-(9Ci) is a specialized fluorinated catechol derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its unique trifluoroethanol-substituted phenolic structure, which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers and resins with tailored surface properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create chelating ligands for asymmetric catalysis and metal complexation.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) in fluorinated aromatic compounds.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for high-purity, complex organic molecules.

Basic Information

Item	Detail
Product Name	1,2-Benzenediol,4-(2,2,2-Trifluoro-1-Hydroxyethyl)-(9Ci)
CAS No.	352339-80-1
Molecular Formula	C8H7F3O3
Molecular Weight	208.14 g/mol
Synonyms	4-(2,2,2-Trifluoro-1-hydroxyethyl)benzene-1,2-diol; 4-(2,2,2-Trifluoro-1-hydroxyethyl)catechol; 2,3-Dihydroxybenzyl Alcohol, α-(Trifluoromethyl)-; 1,2-Dihydroxy-4-(2,2,2-trifluoro-1-hydroxyethyl)benzene; (2,2,2-Trifluoro-1-(3,4-dihydroxyphenyl)ethanol; TFH-Catechol; CAS 352339-80-1
EINECS	Contact for details

Quality Control

Our 1,2-Benzenediol,4-(2,2,2-Trifluoro-1-Hydroxyethyl)-(9Ci) is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.