Description

6-Bromo-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule drug candidates targeting various disease pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways.

• Pharmaceutical Intermediate: Core building block for the development of kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the GMP synthesis of candidate drugs during clinical development.
• Biochemical Tool Compound Synthesis: Utilized to create probes for studying biological mechanisms and enzyme functions.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents.

Basic Information

Product Name	6-Bromo-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	352328-87-1
Molecular Formula	C8H6BrN3OS
Molecular Weight	272.12 g/mol
Synonyms	6-Bromo-2-(methylthio)-8H-pyrido[2,3-d]pyrimidin-7-one; 6-Bromo-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one; 352328-87-1; 6-Bromo-2-(methylmercapto)pyrido[2,3-d]pyrimidin-7(8H)-one; 6-Bromo-2-(methylthio)pyrido[2,3-d]pyrimidin-7-ol (tautomer); Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-bromo-2-(methylthio)-
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.