Description

5-Bromo-1-(2,6-Difluoro-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex, high-value APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery programs.

Basic Information

Product Name	5-Bromo-1-(2,6-Difluoro-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione
CAS No.	352303-66-3
Molecular Formula	C₁₂H₉BrF₂N₂O₂
Molecular Weight	331.11 g/mol
Synonyms	5-Bromo-1-(2,6-difluorobenzyl)-6-methylpyrimidine-2,4(1H,3H)-dione; 5-Bromo-1-(2,6-difluorobenzyl)-6-methyluracil; 352303-66-3; 1-(2,6-Difluorobenzyl)-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione; 5-Bromo-1-(2,6-difluorobenzyl)-6-methyl-1H-pyrimidine-2,4(1H,3H)-dione; 5-Bromo-6-methyl-1-(2,6-difluorobenzyl)uracil
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(2,6-Difluoro-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.