Description

1-(2,6-Difluoro-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione is a high-purity, fluorinated pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Research: Used as a building block for developing new herbicides and fungicides, leveraging its fluorinated aromatic structure.
• Chemical Synthesis: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential intermediate for the synthesis of specialty polymers and advanced organic materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Item	Details
Product Name	1-(2,6-Difluoro-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione
CAS No.	352303-65-2
Molecular Formula	C12H10F2N2O2
Molecular Weight	252.22 g/mol
Synonyms	6-Methyl-1-(2,6-difluorobenzyl)uracil; 1-(2,6-Difluorobenzyl)-6-methyluracil; 1-(2,6-Difluorobenzyl)-6-methylpyrimidine-2,4(1H,3H)-dione; 6-Methyl-1-(2,6-difluorobenzyl)-1H-pyrimidine-2,4-dione; 352303-65-2; Difluorobenzyl Methyluracil Derivative
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorobenzyl)-6-methyluracil is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.