Description

H-Ala-Tyr-Pro-Gly-Lys-Phe-Nh2 is a synthetic hexapeptide amide, a sequence of six amino acids with a C-terminal amide modification. This compound is of significant interest in pharmaceutical research and development, particularly for studying peptide structure-activity relationships and as a potential intermediate for novel therapeutic agents. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on peptide-based drug discovery, metabolic studies, and biochemical assays.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and synthesis of novel peptide-based therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Structure-Activity Relationship (SAR) Studies: Essential for modifying peptide sequences to optimize biological activity, stability, and pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide chemistry, molecular biology, and medicinal chemistry.
• Bioconjugation & Labeling: Acts as a building block for creating labeled peptides used in diagnostic assays or imaging probes.
• Peptide Library Synthesis: Used in the combinatorial synthesis of peptide libraries for high-throughput screening against biological targets.

Basic Information

Product Name	H-Ala-Tyr-Pro-Gly-Lys-Phe-Nh2
CAS No.	352017-71-1
Molecular Formula	C35H49N9O8
Molecular Weight	723.82 g/mol
Synonyms	Ala-Tyr-Pro-Gly-Lys-Phe-NH2; AYPGLKF-NH2; Hexapeptide amide AYPGLKF; H-Ala-Tyr-Pro-Gly-Lys-Phe-amide; AT-1 (research code); L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; [Ala1,Tyr2,Pro3,Gly4,Lys5,Phe6]-NH2 peptide
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Ala-Tyr-Pro-Gly-Lys-Phe-Nh2 undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for active pharmaceutical ingredients (APIs) and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.