Description

3-Hydrazinyl-2-Methyl-7,8-Dihydro-6H-Cyclopenta[2,3]Thieno[2,4-B]Pyrimidin-1-One CAS NO 351342-00-2 is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, small-molecule drug candidates, particularly in therapeutic areas requiring targeted inhibition. It is primarily sought after by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in medicinal chemistry and early-stage drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds to study specific biological pathways.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and process development stages for new chemical entities (NCEs).
• Contract Manufacturing: Supplied to CDMOs for custom synthesis projects under cGMP or non-GMP conditions.
• Academic Research: Utilized in university laboratories for investigating novel heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	3-Hydrazinyl-2-Methyl-7,8-Dihydro-6H-Cyclopenta[2,3]Thieno[2,4-B]Pyrimidin-1-One
CAS No.	351342-00-2
Molecular Formula	C11H13N5OS
Molecular Weight	263.32 g/mol
Synonyms	3-Hydrazinyl-2-methyl-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-1(2H)-one; 2-Methyl-3-hydrozinyl-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-1-one; Cyclopenta[2,3]thieno[2,4-b]pyrimidin-1-one, 3-hydrozinyl-2-methyl-7,8-dihydro-6H-; CAS 351342-00-2; Thienopyrimidine derivative, 3-hydrozinyl; Advanced pharmaceutical intermediate 351342-00-2
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistent purity and structural integrity, which is critical for downstream pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are supplied with each shipment. Our quality commitment aligns with the standards expected by the pharmaceutical industry for non-GMP and cGMP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.