Description

3-(3,4-Dichlorophenyl)-6-Methyl-4-Methylene-3,4-Dihydro-2(1H)-Quinazolinone is a specialized heterocyclic organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its unique quinazolinone core, functionalized with dichlorophenyl and methylene groups, makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its dichlorophenyl moiety for enhanced bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and receptor-ligand interactions in biochemical assays.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic chemistry research and custom synthesis projects.
• Process Chemistry Development: Employed in route scouting and optimization studies for the efficient, scalable production of complex target molecules.

Basic Information

Product Name	3-(3,4-Dichlorophenyl)-6-Methyl-4-Methylene-3,4-Dihydro-2(1H)-Quinazolinone
CAS No.	351225-49-5
Molecular Formula	C₁₆H₁₂Cl₂N₂O
Molecular Weight	319.19 g/mol
Synonyms	3-(3,4-Dichlorophenyl)-6-methyl-4-methylidene-3,4-dihydro-1H-quinazolin-2-one; 4-Methylene-3-(3,4-dichlorophenyl)-6-methyl-3,4-dihydroquinazolin-2(1H)-one; 351225-49-5; Quinazolinone, 3-(3,4-dichlorophenyl)-6-methyl-4-methylene-3,4-dihydro-2(1H)-; 3,4-Dihydro-3-(3,4-dichlorophenyl)-6-methyl-4-methylene-2(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our production of 3-(3,4-Dichlorophenyl)-6-Methyl-4-Methylene-3,4-Dihydro-2(1H)-Quinazolinone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.