Description

(tert-Butoxy)Carbonyl Dl-Phe(4-Nhfmoc)-Oh is a specialized, dual-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity during complex solid-phase and solution-phase peptide assembly. It is primarily utilized in the pharmaceutical, biotechnology, and academic research sectors for the development of novel therapeutic peptides and peptidomimetics.

Application

• Peptide Synthesis Building Block: Serves as a key intermediate in the stepwise construction of complex peptides, particularly where orthogonal protection of the phenylalanine side chain is required.
• Pharmaceutical Research & Development: Used in the discovery and development of new peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Academic & Institutional Research: A valuable reagent for studying peptide structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	(tert-Butoxy)Carbonyl Dl-Phe(4-Nhfmoc)-Oh
CAS No.	351208-71-4
Molecular Formula	C30H30N2O6
Molecular Weight	514.57 g/mol
Synonyms	Boc-DL-Phe(4-NHFmoc)-OH; N-α-Boc-N-ε-(9-Fluorenylmethoxycarbonyl)-DL-4-aminophenylalanine; Boc-4-(Fmoc-amino)-DL-phenylalanine; DL-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-[1-[[4-[(9H-fluoren-9-ylmethoxy)formamido]phenyl]methyl]-2-carboxyethyl]carbamate; Fmoc-4-amino-DL-Phe(Boc)-OH; DL-Phenylalanine, 4-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl Dl-Phe(4-Nhfmoc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and production applications. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.