Description

2-Chloro-3-Nitro-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-value, heterocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fused pyrido-pyrimidinone scaffold makes it a versatile building block for constructing complex molecules with potential biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science Precursor: Potential starting material for the synthesis of specialized organic electronic materials or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects requiring this specific heterocycle.

Basic Information

Product Name	2-Chloro-3-Nitro-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	349573-14-4
Molecular Formula	C8H4ClN3O3
Molecular Weight	225.59 g/mol
Synonyms	2-Chloro-3-nitropyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 2-chloro-3-nitro-; 349573-14-4; 2-Chloro-3-nitro-4H-pyrido[1,2-a]pyrimidin-4-one; Pyrido[1,2-a]pyrimidin-4-one, 2-chloro-3-nitro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.