Description

2(1H)-Pyrimidinone,5-Acetyl-4-(5-Chloro-2-Hydroxyphenyl)-3,4-Dihydro-6-Methyl-(9Ci) CAS NO 349493-14-7 is a high-purity, functionalized dihydropyrimidinone derivative, a key heterocyclic scaffold in advanced organic synthesis. This compound is valued for its structural complexity, which makes it an essential pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its modifiable acetyl, chloro, and hydroxyl functional groups.
• Agrochemical Development: Acts as a key intermediate in the research and synthesis of new herbicides, fungicides, or plant growth regulators.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Academic & Institutional R&D: Utilized in universities and research institutes for exploring novel heterocyclic chemistry and reaction methodologies.

Basic Information

Item	Details
Product Name	2(1H)-Pyrimidinone,5-Acetyl-4-(5-Chloro-2-Hydroxyphenyl)-3,4-Dihydro-6-Methyl-(9Ci)
CAS No.	349493-14-7
Molecular Formula	C13H13ClN2O3
Molecular Weight	280.71 g/mol
Synonyms	5-Acetyl-4-(5-chloro-2-hydroxyphenyl)-3,4-dihydro-6-methyl-2(1H)-pyrimidinone; 4-(5-Chloro-2-hydroxyphenyl)-5-acetyl-3,4-dihydro-6-methyl-2(1H)-pyrimidinone; 5-Acetyl-4-(5-chloro-2-hydroxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 349493-14-7; Dihydropyrimidinone derivative; Chlorohydroxyphenyl acetyl pyrimidinone
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.