Description

2-Chloro-n-(4-(n-(4-Methylpyrimidin-2-Yl)Sulfamoyl)Phenyl)-5-Nitrobenzamide is a high-purity, synthetic organic compound featuring a complex molecular architecture combining sulfonamide, pyrimidine, and benzamide pharmacophores. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or precursor for novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical synthesis companies engaged in the discovery of new therapeutic agents, especially in areas targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, particularly for targeted therapies.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic inhibition studies and structure-activity relationship (SAR) research.
• Organic Synthesis: Acts as a versatile precursor for further chemical modifications due to its reactive chloro, nitro, and sulfonamide functional groups.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new chemical entities.

Basic Information

Product Name	2-Chloro-n-(4-(n-(4-Methylpyrimidin-2-Yl)Sulfamoyl)Phenyl)-5-Nitrobenzamide
CAS No.	349145-23-9
Molecular Formula	C19H14ClN5O5S
Molecular Weight	463.86 g/mol
Synonyms	2-Chloro-N-[4-[[(4-methyl-2-pyrimidinyl)amino]sulfonyl]phenyl]-5-nitrobenzamide; 2-Chloro-5-nitro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]benzamide; 349145-23-9; Benzamide, 2-chloro-N-[4-[[(4-methyl-2-pyrimidinyl)amino]sulfonyl]phenyl]-5-nitro-; N-(4-(N-(4-Methylpyrimidin-2-yl)sulfamoyl)phenyl)-2-chloro-5-nitrobenzamide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-n-(4-(n-(4-Methylpyrimidin-2-Yl)Sulfamoyl)Phenyl)-5-Nitrobenzamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.