Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(2-Thienyl)-,1-Methylethylester(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging its unique pyrimidine-thiophene hybrid structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds for material science or catalysis research.
• Process Chemistry & Scale-Up: Utilized in process optimization and pilot-scale production for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(2-Thienyl)-,1-Methylethylester(9Ci)
CAS No.	346716-72-1
Molecular Formula	C13H16N2O3S
Molecular Weight	280.34 g/mol
Synonyms	1-Methylethyl 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-thienyl)-5-pyrimidinecarboxylate; Isopropyl 4-(thiophen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 4-(2-Thienyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid isopropyl ester; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-thienyl)-, 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a quality management system and can supply material tailored to specific project requirements, including those for pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.