Description

2-Methoxyethyl 4-(3-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel dihydropyrimidinone (DHPM) derivatives, a class of compounds with diverse biological activities.
• Drug Discovery & Development: Used in medicinal chemistry research for the construction of targeted molecular libraries and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of client-specific compounds and non-commercial APIs.
• Chemical Research: Serves as a model substrate in organic synthesis studies, particularly for Biginelli reaction derivatives and heterocyclic chemistry.
• Agrochemical Research: Potential intermediate for developing new crop protection agents, leveraging the bioactive dihydropyrimidinone core structure.

Basic Information

Product Name	2-Methoxyethyl 4-(3-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	346715-15-9
Molecular Formula	C₁₆H₂₀N₂O₅
Molecular Weight	320.34 g/mol
Synonyms	2-Methoxyethyl 4-(3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(3-Methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic Acid 2-Methoxyethyl Ester; DHPM Derivative; Biginelli Reaction Product; 5-Carbethoxy-4-(3-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one 2-Methoxyethyl Ester; CAS 346715-15-9
EINECS	Contact for details

Quality Control

Our 2-Methoxyethyl 4-(3-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.