Description

Boc-L-β-Homolysine(Cbz) is a protected, non-proteinogenic amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of a modified lysine side chain, enabling the development of novel peptides and peptidomimetics with enhanced properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications in drug discovery and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based therapeutics and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a homologated lysine residue with orthogonal protecting groups (Boc and Cbz).
• Bioconjugation & Labeling: Serves as a specialized linker or spacer molecule for attaching labels, probes, or other functional groups to biomolecules.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of enzyme inhibitors by mimicking natural amino acid structures.
• Material Science: Can be utilized in the creation of functionalized polymers and smart materials with specific biological recognition properties.

Basic Information

Item	Detail
Product Name	Boc-L-β-Homolysine(Cbz)
CAS No.	346694-77-7
Molecular Formula	C20H30N2O6
Molecular Weight	394.47 g/mol
Synonyms	Nα-Boc-Nε-Cbz-L-β-Homolysine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic Acid (common mis-assignment check); Boc-Lys(Cbz)-OH (β-homo variant); tert-Butyl (S)-(6-(((benzyloxy)carbonyl)amino)-1-carboxy-5-oxohexyl)carbamate; Nα-Boc-Nε-Z-L-β-Homolysine; Boc-β-homo-Lys(Cbz)-OH; Fmoc-L-β-Homolysine(Boc) (related, different protection); Amino Acid Derivative CAS 346694-77-7
EINECS	Contact for details

Quality Control

Our Boc-L-β-Homolysine(Cbz) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.