Description

1-[(2-Fluorophenyl)Methyl]-1H-Indole-2,3-Dione is a specialized fluorinated isatin derivative, a key heterocyclic scaffold in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. Researchers and process chemists in pharmaceutical R&D, agrochemical discovery, and material science need this high-purity intermediate to synthesize new active compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Organic Synthesis Reagent: Used in various name reactions and as a starting material for constructing complex heterocyclic systems, including spirooxindoles and fused indole derivatives.
• Material Science Precursor: Employed in the research and development of organic electronic materials, dyes, and photoactive compounds.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor-ligand interactions.

Basic Information

Product Name	1-[(2-Fluorophenyl)Methyl]-1H-Indole-2,3-Dione
CAS No.	346640-52-6
Molecular Formula	C15H10FNO2
Molecular Weight	255.25 g/mol
Synonyms	1-(2-Fluorobenzyl)indoline-2,3-dione; 1-(2-Fluorobenzyl)isatin; 2-Fluorobenzylisatin; 1-(2-Fluorobenzyl)-1H-indole-2,3-dione; 1-(2-Fluorobenzyl)-2,3-dioxoindoline; Isatin, 1-(2-fluorobenzyl)-; 346640-52-6; 1-(2-Fluorobenzyl)indole-2,3-dione
EINECS	Contact for details

Quality Control

Our 1-[(2-Fluorophenyl)Methyl]-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.