Description

3-(4-Amino-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Phenol is a high-purity, heterocyclic organic compound featuring a fused pyrrolopyrimidine core. This advanced pharmaceutical intermediate is critical for the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent and selective kinase inhibitors for targeted cancer therapies.
• Oncology Drug Discovery: Serves as a core scaffold in medicinal chemistry programs focused on tyrosine kinase inhibitors (TKIs) and other signaling pathway modulators.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Anti-inflammatory Agent Development: Explored as a precursor for compounds targeting inflammatory pathways such as JAK/STAT.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of heterocyclic compounds.

Basic Information

Product Name	3-(4-Amino-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Phenol
CAS No.	344359-60-0
Molecular Formula	C12H10N4O
Molecular Weight	226.23 g/mol
Synonyms	5-(3-Hydroxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 3-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenol; 4-Amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4-amino-5-(3-hydroxyphenyl)-7H-; CAS 344359-60-0
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.