Description

2(1H)-Pyrimidinone,5-Fluoro-3,4-Dihydro-1,3-Dimethyl-4-Methylene-(9Ci) is a specialized fluorinated pyrimidinone derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-substituted heterocyclic core enables precise molecular tuning. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries focused on creating next-generation compounds with enhanced biological activity and selectivity. The CAS number for this material is 344326-28-9.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel fluorinated drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances stability and bioactivity.
• Fine Chemical Building Block: Employed in custom synthesis and research for creating complex heterocyclic compounds with specific electronic properties.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and advanced organic electronic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to study enzyme interactions and structure-activity relationships (SAR).

Basic Information

Product Name	2(1H)-Pyrimidinone,5-Fluoro-3,4-Dihydro-1,3-Dimethyl-4-Methylene-(9Ci)
CAS No.	344326-28-9
Molecular Formula	C7H9FN2O
Molecular Weight	156.16 g/mol
Synonyms	5-Fluoro-3,4-dihydro-1,3-dimethyl-4-methylene-2(1H)-pyrimidinone; 5-Fluoro-1,3-dimethyl-4-methylenepyrimidin-2(1H)-one; 344326-28-9; 5-Fluoro-1,3-dimethyl-4-methylenepyrimidin-2-one; 4-Methylene-5-fluoro-1,3-dimethyl-3,4-dihydropyrimidin-2(1H)-one; 5-Fluoro-1,3-dimethyl-4-methylenepyrimidin-2(1H)-one (9CI)
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone,5-Fluoro-3,4-Dihydro-1,3-Dimethyl-4-Methylene-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure storage areas are free from such contaminants. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.