Description

Cyclopropanecarboxylic Acid, 1-Fluoro-2-(1-Methylethyl)-, Ethyl Ester (9Ci) is a specialized fluorinated cyclopropane derivative, a high-value building block prized for its unique three-membered ring structure and fluorine substituent. This compound matters for its role in enabling complex molecular architectures, offering significant potential for modulating the biological activity, metabolic stability, and physical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane and fluorine motifs can enhance potency and environmental profile.
• Advanced Material Precursor: Serves as a building block for specialty polymers and liquid crystals, where its rigid structure influences material properties.
• Chemical Biology Probe Development: Employed in the synthesis of labeled compounds or molecular probes for studying biological mechanisms and target engagement.
• Process Chemistry & Scale-Up: Suitable for use in route scouting and optimization for the commercial production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for methodology development in organic synthesis, particularly in fluorination and cyclopropanation chemistry.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxylic Acid, 1-Fluoro-2-(1-Methylethyl)-, Ethyl Ester (9Ci)
CAS No.	343867-06-1
Molecular Formula	C9H15FO2
Molecular Weight	174.21 g/mol
Synonyms	Ethyl 1-Fluoro-2-isopropylcyclopropanecarboxylate; 1-Fluoro-2-isopropylcyclopropanecarboxylic Acid Ethyl Ester; 1-Fluoro-2-(1-methylethyl)cyclopropanecarboxylic Acid Ethyl Ester; 343867-06-1; Cyclopropanecarboxylic acid, 1-fluoro-2-(1-methylethyl)-, ethyl ester; Ethyl 1-fluoro-2-(propan-2-yl)cyclopropane-1-carboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Fluoro-2-(1-Methylethyl)-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and GC-MS and NMR for structural confirmation, to ensure compliance with precise specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Handle and store under an inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.