Description

3-(3-Pyridyl)-L-Alanine Hydrochloride is a high-purity, non-natural amino acid derivative used as a critical building block in advanced chemical synthesis. This compound is valued for its role in introducing a pyridyl functional group into peptide chains and other complex molecules, enabling the development of novel bioactive compounds. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide synthesis, and the development of enzyme inhibitors and receptor ligands.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a functionalized pyridyl side chain.
• Biochemical Research: Serves as a substrate analog or inhibitor in enzymatic studies and proteomics research.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to modulate the properties of lead compounds.
• Ligand Development: Useful for creating chelating agents or metal-binding motifs in coordination chemistry.
• Academic & Industrial R&D: A versatile reagent for exploring novel chemical space in organic and bioorganic chemistry projects.

Basic Information

Product Name	3-(3-Pyridyl)-L-Alanine Hydrochloride
CAS No.	343626-03-9
Molecular Formula	C8H10N2O2 · HCl
Molecular Weight	202.63 g/mol
Synonyms	L-3-(3-Pyridyl)alanine hydrochloride; (S)-2-Amino-3-(3-pyridyl)propionic acid hydrochloride; 3-(3-Pyridinyl)-L-alanine hydrochloride; β-(3-Pyridyl)-L-alanine HCl; 3-Pyridin-3-yl-L-alanine hydrochloride; H-3-Pal(3)-OH · HCl
EINECS	Contact for details

Quality Control

Our 3-(3-Pyridyl)-L-Alanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.