Description

3',4'-Difluorobiphenyl-3-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound is a critical intermediate in advanced organic synthesis, valued for its unique biphenyl core and strategically placed fluorine atoms and formyl group. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the difluorobiphenyl moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and optical properties.
• Cross-Coupling Reactions: The aldehyde group is amenable to further functionalization via reactions like reductive amination or Wittig olefination, enabling rapid library synthesis.
• Academic & Contract Research: Employed in methodological studies and as a standard in analytical chemistry for novel synthetic route development.

Basic Information

Product Name	3',4'-Difluorobiphenyl-3-Carbaldehyde
CAS No.	343604-41-1
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	3-(3,4-Difluorophenyl)benzaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 3',4'-difluoro-; 3-Formyl-3',4'-difluorobiphenyl; 3',4'-Difluoro-[1,1'-biphenyl]-3-carbaldehyde; 3-Carbaldehyde-3',4'-difluorobiphenyl
EINECS	Contact for details

Quality Control

Our 3',4'-Difluorobiphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.