Description

D-Klvffa CAS NO 342877-55-8 is a high-purity synthetic peptide sequence of significant interest in advanced biochemical and pharmaceutical research. This compound is valued for its specific structural properties, which make it a critical tool for studying protein-protein interactions and aggregation mechanisms. It is primarily utilized by research institutions and pharmaceutical developers focused on neurodegenerative diseases and amyloid research. Our supply ensures consistent quality and reliable availability for critical global R&D projects.

Application

• Biomedical Research: Used as a key reagent in studies of amyloid-beta peptide aggregation and neurotoxicity, relevant to Alzheimer's disease research.
• Drug Discovery Screening: Serves as a reference standard or target molecule in high-throughput screening assays for potential therapeutic inhibitors.
• Biophysical Studies: Employed in spectroscopic analysis (e.g., NMR, CD spectroscopy) to investigate peptide conformation, stability, and folding dynamics.
• Antibody Development: Acts as an antigen for the production and characterization of specific antibodies targeting amyloid-related epitopes.
• Academic & Institutional Research: Provides a well-defined model system for university labs and research centers studying protein misfolding disorders.
• Diagnostic Development: Potential use in the calibration and validation of diagnostic assays designed to detect amyloidogenic peptides.

Basic Information

Product Name	D-Klvffa
CAS No.	342877-55-8
Molecular Formula	C36H52N8O7
Molecular Weight	708.86 g/mol
Synonyms	D-KLVFFA-NH2; D-enantiomer of KLVFFA; D-Lys-L-Val-Phe-Phe-Ala; H-D-Lys-D-Leu-D-Val-D-Phe-D-Phe-D-Ala-NH2; Amyloid β-Protein (16-20) D-isomer; Aβ(16-20) D-form; Inverse sequence peptide; All-D-KLVFFA
EINECS	Contact for details

Quality Control

Every batch of D-Klvffa is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing purity, HPLC chromatograms, and mass spectrometry data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the product should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store under inert atmosphere if the container is opened frequently.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Acetic Acid; Sparingly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.