Description

Ethyl 4-(3-Fluorophenyl)-1,6-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery programs. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic compounds with specific biological activity.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for studying synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	Ethyl 4-(3-Fluorophenyl)-1,6-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate
CAS No.	342596-78-5
Molecular Formula	C15H17FN2O3
Molecular Weight	292.31 g/mol
Synonyms	Ethyl 4-(3-fluorophenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(3-fluorophenyl)-1,6-dimethyl-2-oxo-, ethyl ester; 342596-78-5; 4-(3-Fluorophenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 4-(3-fluorophenyl)-1,6-dimethyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Fluorophenyl)-1,6-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.