Description

3-[(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Amino]Propan-1-Ol CAS NO 342595-53-3 is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, targeted therapeutic agents, particularly kinase inhibitors. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors focused on oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent and selective kinase inhibitors for targeted cancer therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Development: Used in the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) with thienopyrimidine cores.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition mechanisms and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	3-[(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Amino]Propan-1-Ol
CAS No.	342595-53-3
Molecular Formula	C15H15N3OS
Molecular Weight	285.36 g/mol
Synonyms	4-[(3-Hydroxypropyl)amino]-5-phenylthieno[2,3-d]pyrimidine; 3-[(5-Phenylthieno[2,3-d]pyrimidin-4-yl)amino]-1-propanol; 5-Phenyl-N-(3-hydroxypropyl)thieno[2,3-d]pyrimidin-4-amine; Thieno[2,3-d]pyrimidin-4-amine, 5-phenyl-N-3-hydroxypropyl-; 342595-53-3; 3-(5-Phenylthieno[2,3-d]pyrimidin-4-ylamino)propan-1-ol
EINECS	Contact for details

Quality Control

Our 3-[(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Amino]Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for each lot, supporting compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.