Description

3-Amino-2-Ethyl-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures due to its reactive amino and carbonyl functional groups.
• Research & Development (R&D): Essential for academic and industrial research focused on exploring new chemical entities and structure-activity relationships (SAR).
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.
• Biochemical Research: Potential utility as a tool compound or ligand in biochemical assays and proteomics studies.

Basic Information

Product Name	3-Amino-2-Ethyl-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One
CAS No.	342383-93-1
Molecular Formula	C11H13N3OS
Molecular Weight	235.31 g/mol
Synonyms	3-Amino-2-ethyl-4-oxo-3,4,5,6,7,8-hexahydrocyclopenta[4,5]thieno[2,3-d]pyrimidine; 2-Ethyl-3-amino-4-oxo-3,4,5,6,7,8-hexahydrocyclopenta[4,5]thieno[2,3-d]pyrimidine; Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one, 3-amino-2-ethyl-3,5,6,7-tetrahydro-4H-; 342383-93-1; 3-Amino-2-ethyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 3-Amino-2-Ethyl-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All materials are manufactured and tested in facilities that follow cGMP principles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, purity (typically ≥98% by HPLC), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.