Description

5-(Benzyloxy)-2-Fluoroaniline is a specialized aromatic amine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected phenol and a fluorine substituent on the aniline ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular framework of charge-transport or emissive layers.
• Dye & Pigment Chemistry: Employed in the synthesis of specialized dyes and colorants, where the aniline moiety is integral to chromophore development.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	5-(Benzyloxy)-2-Fluoroaniline
CAS No.	342042-82-4
Molecular Formula	C₁₃H₁₂FNO
Molecular Weight	217.24 g/mol
Synonyms	2-Fluoro-5-(phenylmethoxy)aniline; 2-Fluoro-5-benzyloxyaniline; 5-Benzyloxy-2-fluoroaniline; 2-Amino-4-fluorophenyl benzyl ether; Benzenemethanamine, 5-(benzyloxy)-2-fluoro-; 342042-82-4; 5-(Benzyloxy)-2-fluoro-benzenamine
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.