Description

2,4-Dioxo-1-(4-Pyridinylmethyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity heterocyclic building block and advanced pharmaceutical intermediate. This compound is valued for its unique pyrimidine-pyridine hybrid structure, which serves as a critical scaffold in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and synthesis of potential kinase inhibitors due to its privileged heterocyclic structure.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis Building Block: Provides a specialized starting material for contract research organizations (CROs) and fine chemical manufacturers.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,4-Dioxo-1-(4-Pyridinylmethyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	341966-23-2
Molecular Formula	C12H10N4O2
Molecular Weight	242.24 g/mol
Synonyms	1-[(Pyridin-4-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Cyano-1-(4-pyridylmethyl)dihydrouracil; 1-(4-Pyridinylmethyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Cyano-1-(pyridin-4-ylmethyl)pyrimidine-2,4(1H,3H)-dione; Dihydrouracil-5-carbonitrile, 1-(4-pyridinylmethyl)-; CAS 341966-23-2
EINECS	Contact for details

Quality Control

Our 2,4-Dioxo-1-(4-Pyridinylmethyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.