Description

1-[4-(Trifluoromethyl)Benzyl]Homopiperazine, 95% is a high-purity, trifluoromethyl-substituted benzyl homopiperazine derivative, a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this privileged scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Useful for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Benzyl]Homopiperazine, 95%
CAS No.	340759-28-6
Molecular Formula	C13H17F3N2
Molecular Weight	258.28 g/mol
Synonyms	1-[(4-(Trifluoromethyl)phenyl)methyl]hexahydro-1H-1,4-diazepine; 1-(4-(Trifluoromethyl)benzyl)homopiperazine; Hexahydro-1-[(4-(trifluoromethyl)phenyl)methyl]-1H-1,4-diazepine; 1-(4-Trifluoromethylbenzyl)homopiperazine; 1-(alpha,alpha,α-Trifluoro-p-tolyl)homopiperazine; Homopiperazine, 1-[(4-(trifluoromethyl)phenyl)methyl]-; 1-(4-Trifluoromethyl-benzyl)-[1,4]diazepane
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Benzyl]Homopiperazine, 95% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.