Description

(5Z)-5-{[2,5-Dimethyl-1-(4-Methylphenyl)-1H-Pyrrol-3-Yl]Methylidene}-1-(Prop-2-En-1-Yl)-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), offering researchers and manufacturers a reliable and well-defined starting material. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of proprietary drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients.
• Biochemical Research: Acts as a specialized reagent or inhibitor in biochemical pathway studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	(5Z)-5-{[2,5-Dimethyl-1-(4-Methylphenyl)-1H-Pyrrol-3-Yl]Methylidene}-1-(Prop-2-En-1-Yl)-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione
CAS No.	340230-22-0
Molecular Formula	C22H21N3O2S
Molecular Weight	391.49 g/mol
Synonyms	1-Allyl-5-[(2,5-dimethyl-1-p-tolylpyrrol-3-yl)methylene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 5-[(2,5-Dimethyl-1-(4-methylphenyl)-1H-pyrrol-3-yl)methylene]-1-(2-propen-1-yl)-2-thioxo-4,6(1H,5H)-pyrimidinedione; (5Z)-1-Allyl-5-[(2,5-dimethyl-1-p-tolyl-1H-pyrrol-3-yl)methylene]-2-thioxo-1,2,3,4-tetrahydropyrimidine-4,6-dione; CAS 340230-22-0; Pyrrolopyrimidinedione derivative; Thioxodihydropyrimidinedione intermediate.
EINECS	Contact for details

Quality Control

Our (5Z)-5-{[2,5-Dimethyl-1-(4-Methylphenyl)-1H-Pyrrol-3-Yl]Methylidene}-1-(Prop-2-En-1-Yl)-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.