Description

1-(3,4-Dichlorophenyl)-6-Hydroxy-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One is a high-purity, heterocyclic organic compound featuring a pyrimidinone core with dichlorophenyl and thioxo functional groups. This specialized chemical serves as a critical pharmaceutical intermediate and research building block for the synthesis of novel active molecules. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Used in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions.
• Material Science: Intermediate for creating specialized polymers or organic electronic materials with unique properties.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting heterocyclic chemistry research.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under GMP-like conditions.

Basic Information

Product Name	1-(3,4-Dichlorophenyl)-6-Hydroxy-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One
CAS No.	340216-43-5
Molecular Formula	C10H6Cl2N2O2S
Molecular Weight	289.14 g/mol
Synonyms	6-Hydroxy-1-(3,4-dichlorophenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-(3,4-Dichlorophenyl)-6-hydroxy-2-mercapto-3,4-dihydropyrimidin-4-one; 4(1H)-Pyrimidinone, 1-(3,4-dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydro-; CAS 340216-43-5; 6-Hydroxy-1-(3,4-dichlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one; 1-(3,4-Dichlorophenyl)-6-hydroxy-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dichlorophenyl)-6-Hydroxy-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.