Description

β-Sheet Breaker Peptide CAS NO 339990-32-8 is a synthetic peptide specifically designed to disrupt the formation of β-sheet structures, which are implicated in the pathogenesis of various amyloid diseases. This compound is a critical research tool for investigating protein misfolding and aggregation mechanisms. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on neurodegenerative disease research and therapeutic development.

Application

• Neurodegenerative Disease Research: Fundamental studies on the inhibition of amyloid-beta (Aβ) aggregation associated with Alzheimer's disease.
• Therapeutic Candidate Screening: Evaluation of peptide efficacy and mechanism of action in cellular and animal models of amyloidosis.
• Biophysical Studies: Investigation of protein-protein interactions, aggregation kinetics, and structural biology using techniques like spectroscopy and microscopy.
• Prion Disease Research: Exploration of agents capable of interfering with prion protein aggregation and fibril formation.
• Drug Discovery Platforms: Serving as a reference compound or lead structure in high-throughput screening assays for anti-aggregation agents.
• Formulation Development: Studies on the stability, delivery, and bioavailability of peptide-based therapeutic candidates.

Basic Information

Product Name	β-Sheet Breaker Peptide CAS NO 339990-32-8
CAS No.	339990-32-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-Sheet Inhibitor Peptide; Amyloid-beta Aggregation Inhibitor; Aβ Aggregation Blocker; iAβ5p Peptide; β-Breaker Peptide; Amyloid Interfering Peptide; Protein Misfolding Inhibitor; Research Peptide 339990-32-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.