Description

4-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-2-Pyrimidinamine is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its molecular architecture, featuring a chlorophenyl-thiazole core fused with a pyrimidinamine group, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology & Proteomics: Employed as a molecular probe or scaffold in studying protein-ligand interactions and enzyme inhibition.
• Material Science Precursor: Serves as a starting material for creating specialized organic electronic materials or ligands for catalysis.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	4-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-2-Pyrimidinamine
CAS No.	339279-50-4
Molecular Formula	C13H9ClN4S
Molecular Weight	288.75 g/mol
Synonyms	4-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]pyrimidin-2-amine; 2-Amino-4-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]pyrimidine; 4-(2-(4-Chlorophenyl)thiazol-5-yl)pyrimidin-2-amine; 339279-50-4; 4-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-2-aminopyrimidine; 5-(2-Aminopyrimidin-4-yl)-2-(4-chlorophenyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our production of 4-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-2-Pyrimidinamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.