Description

4-([3-(Trifluoromethyl)Phenyl]Sulfanyl)Aniline is a specialized aromatic amine derivative featuring a phenylsulfanyl linker and a trifluoromethyl substituent. This compound is a valuable high-purity intermediate for advanced chemical synthesis, prized for its unique electronic and steric properties imparted by the sulfur and fluorine atoms. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams seeking to incorporate this distinct molecular scaffold into novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for targets requiring specific lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common bioisostere.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as an aniline derivative for constructing complex heterocyclic and sulfur-containing compounds.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry optimization in both academic and industrial settings.

Basic Information

Product Name	4-([3-(Trifluoromethyl)Phenyl]Sulfanyl)Aniline
CAS No.	339104-66-4
Molecular Formula	C13H10F3NS
Molecular Weight	269.29 g/mol
Synonyms	4-[(3-Trifluoromethylphenyl)thio]aniline; 4-[(3-Trifluoromethylphenyl)sulfanyl]benzenamine; 1-Amino-4-[(3-trifluoromethylphenyl)thio]benzene; Benzenamine, 4-[(3-(trifluoromethyl)phenyl)thio]-; 4-(3-Trifluoromethylphenylthio)aniline; 4-(α,α,α-Trifluoro-m-tolylthio)aniline; 4-(3-Trifluoromethylphenylsulfanyl)phenylamine
EINECS	Contact for details

Quality Control

Our production of 4-([3-(Trifluoromethyl)Phenyl]Sulfanyl)Aniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is stable under inert atmosphere but should be kept away from strong bases and oxidizing agents. Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.