Description

2-Chlorobenzyl 5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl Sulfide is a high-value, multi-functional chemical building block characterized by its unique aryl sulfide and pyrimidine core. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. Industrial and research chemists in the pharmaceutical, agrochemical, and specialty chemical sectors need this precise intermediate to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the trifluoromethyl group for improved bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, ligands for catalysis, and other functional molecules requiring a tailored aromatic framework.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes and inhibitors to study enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Chlorobenzyl 5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl Sulfide
CAS No.	339101-97-2
Molecular Formula	C18H12ClF3N2S
Molecular Weight	380.81 g/mol
Synonyms	2-(((2-Chlorophenyl)methyl)thio)-5-(3-(trifluoromethyl)phenyl)pyrimidine; 2-Chlorobenzylthio-5-(3-trifluoromethylphenyl)pyrimidine; 5-(3-Trifluoromethylphenyl)-2-((2-chlorobenzyl)thio)pyrimidine; 2-[(2-Chlorobenzyl)sulfanyl]-5-[3-(trifluoromethyl)phenyl]pyrimidine; CAS 339101-97-2
EINECS	Contact for details

Quality Control

Our production of 2-Chlorobenzyl 5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl Sulfide adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.