Description

Ethyl 2-([1-Methyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-2-Pyrimidinyl]Sulfanyl)Acetate is a high-value, sulfur-containing pyrimidine derivative that serves as a critical synthetic intermediate. Its molecular structure, featuring a reactive thioacetate ester and a trifluoromethyl-substituted heterocycle, makes it indispensable for constructing complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and probe development due to its reactive thioester moiety.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development of client-specific molecules.

Basic Information

Product Name	Ethyl 2-([1-Methyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-2-Pyrimidinyl]Sulfanyl)Acetate
CAS No.	339101-93-8
Molecular Formula	C10H11F3N2O3S
Molecular Weight	296.27 g/mol
Synonyms	Ethyl (1-methyl-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl)thioacetate; 2-[(1-Methyl-6-oxo-4-(trifluoromethyl)-1,6-dihydro-2-pyrimidinyl)thio]acetic acid ethyl ester; 1-Methyl-2-[(ethoxycarbonyl)methyl]thio-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidine; 339101-93-8; Ethyl 2-((1-methyl-6-oxo-4-(trifluoromethyl)-1,6-dihydro-2-pyrimidinyl)thio)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-([1-Methyl-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydro-2-Pyrimidinyl]Sulfanyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.