Description

2-[(4-Chlorobenzyl)Sulfanyl]-5-[3-(Trifluoromethyl)Phenyl]Pyrimidine is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS number 339101-71-2. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique heterocyclic structure.
• Chemical Biology Probe: Serves as a tool compound for studying biological pathways and target validation in academic and industrial research settings.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with specific electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-[(4-Chlorobenzyl)Sulfanyl]-5-[3-(Trifluoromethyl)Phenyl]Pyrimidine
CAS No.	339101-71-2
Molecular Formula	C18H12ClF3N2S
Molecular Weight	380.81 g/mol
Synonyms	5-[3-(Trifluoromethyl)phenyl]-2-[(4-chlorophenyl)methyl]sulfanylpyrimidine; 2-((4-Chlorobenzyl)thio)-5-(3-(trifluoromethyl)phenyl)pyrimidine; 2-[(4-Chlorobenzyl)thio]-5-[3-(trifluoromethyl)phenyl]pyrimidine; 339101-71-2; 2-(4-Chlorobenzylsulfanyl)-5-(3-trifluoromethylphenyl)pyrimidine; 2-[(4-Chlorobenzyl)sulfanyl]-5-[3-(trifluoromethyl)phenyl]pyrimidine; 2-(p-Chlorobenzylthio)-5-m-trifluoromethylphenylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-[(4-Chlorobenzyl)Sulfanyl]-5-[3-(Trifluoromethyl)Phenyl]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.