Description

3-Methyl-2-[(4-Methylbenzyl)Sulfanyl]-6-(Trifluoromethyl)-4(3H)-Pyrimidinone CAS NO 339101-58-5 is a specialized heterocyclic compound featuring a pyrimidinone core substituted with a trifluoromethyl group and a methylbenzylsulfanyl moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly in antiviral and anticancer research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its unique trifluoromethyl and sulfur-containing substituents.
• Agrochemical Research: Serves as a core structure for developing novel pesticides and herbicides, leveraging the biological activity of the pyrimidinone scaffold.
• Organic Synthesis Reagent: Employed in specialized organic transformations to introduce complex heterocyclic systems into target molecules.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies targeting specific biological pathways.

Basic Information

Product Name	3-Methyl-2-[(4-Methylbenzyl)Sulfanyl]-6-(Trifluoromethyl)-4(3H)-Pyrimidinone
CAS No.	339101-58-5
Molecular Formula	C₁₄H₁₃F₃N₂OS
Molecular Weight	314.33 g/mol
Synonyms	6-(Trifluoromethyl)-3-methyl-2-[(4-methylbenzyl)thio]-4(3H)-pyrimidinone; 2-[(4-Methylbenzyl)thio]-6-(trifluoromethyl)-3-methyl-4(3H)-pyrimidinone; 3-Methyl-2-[(4-methylbenzyl)thio]-6-(trifluoromethyl)pyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 3-methyl-2-[(4-methylbenzyl)thio]-6-(trifluoromethyl)-; 339101-58-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system adheres to cGMP principles where applicable, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.