Description

Ethyl 2-((5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl)Sulfanyl)Acetate is a high-purity, advanced pharmaceutical intermediate featuring a pyrimidine core with a trifluoromethylphenyl substituent. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides, leveraging the biological activity of the pyrimidine and trifluoromethyl groups.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Material Science: Potential intermediate for creating specialty polymers or functional materials with unique electronic or surface properties.

Basic Information

Product Name	Ethyl 2-((5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl)Sulfanyl)Acetate
CAS No.	339101-32-5
Molecular Formula	C₁₅H₁₃F₃N₂O₂S
Molecular Weight	342.34 g/mol
Synonyms	Ethyl [5-[3-(trifluoromethyl)phenyl]pyrimidin-2-yl]sulfanylacetate; 2-(((5-(3-(Trifluoromethyl)phenyl)pyrimidin-2-yl)thio)acetic acid ethyl ester; Acetic acid, 2-[[5-[3-(trifluoromethyl)phenyl]-2-pyrimidinyl]thio]-, ethyl ester; Ethyl 2-((5-(3-(Trifluoromethyl)phenyl)pyrimidin-2-yl)thio)acetate; CAS 339101-32-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-((5-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinyl)Sulfanyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.