Description

3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Chromen-4-One 3-(Trifluoromethyl)Benzaldehyde Acetal is a specialized organic intermediate featuring a chromanone core with hydroxymethyl and trifluoromethyl benzaldehyde acetal functional groups. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the trifluoromethyl group is prized for its ability to modulate bioactivity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers or advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its reactive hydroxymethyl groups.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Chromen-4-One 3-(Trifluoromethyl)Benzaldehyde Acetal
CAS No.	339029-02-6
Molecular Formula	C20H19F3O5
Molecular Weight	396.36 g/mol
Synonyms	3,3-Bis(hydroxymethyl)-4-chromanone 3-(trifluoromethyl)benzaldehyde acetal; 4H-Chromen-4-one, 2,3-dihydro-3,3-bis(hydroxymethyl)-, 3-(trifluoromethyl)benzaldehyde acetal; Chroman-4-one acetal derivative; α,α-Bis(hydroxymethyl)chroman-4-one acetal; Trifluoromethyl benzaldehyde protected chromanone diol; CAS 339029-02-6
EINECS	Contact for details

Quality Control

Our 3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Chromen-4-One 3-(Trifluoromethyl)Benzaldehyde Acetal is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.