Description

Methyl 3-([(2-Amino-4-Methyl-5-Pyrimidinyl)Carbonyl]Amino)-2-Thiophenecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Research: Employed in the study of biological processes and the development of biochemical probes and inhibitors.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science and agrochemical applications.

Basic Information

Item	Detail
Product Name	Methyl 3-([(2-Amino-4-Methyl-5-Pyrimidinyl)Carbonyl]Amino)-2-Thiophenecarboxylate
CAS No.	339020-63-2
Molecular Formula	C12H12N4O3S
Molecular Weight	292.31 g/mol
Synonyms	Methyl 3-[(2-Amino-4-methylpyrimidine-5-carbonyl)amino]thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[[(2-amino-4-methyl-5-pyrimidinyl)carbonyl]amino]-, methyl ester; Methyl 3-[(2-amino-4-methylpyrimidine-5-amido)]thiophene-2-carboxylate; 339020-63-2; 5-Pyrimidinecarboxamide, 2-amino-N-[3-(methoxycarbonyl)-2-thienyl]-4-methyl-
EINECS	Contact for details

Quality Control

Our production of Methyl 3-([(2-Amino-4-Methyl-5-Pyrimidinyl)Carbonyl]Amino)-2-Thiophenecarboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.