Description

4-Chloro-6-[(4-Fluorophenyl)Sulfanyl]-2-Pyrimidinamine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate its unique halogenated, sulfur-bridged structure into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Chemical Building Block: Employed in organic synthesis for constructing complex molecules due to the reactivity of its chloro and amine groups.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers and advanced materials.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	4-Chloro-6-[(4-Fluorophenyl)Sulfanyl]-2-Pyrimidinamine
CAS No.	339015-98-4
Molecular Formula	C10H7ClFN3S
Molecular Weight	255.70 g/mol
Synonyms	2-Pyrimidinamine, 4-chloro-6-[(4-fluorophenyl)thio]-; 4-Chloro-6-((4-fluorophenyl)thio)pyrimidin-2-amine; 4-Chloro-6-(p-fluorophenylthio)-2-pyrimidinamine; 6-((4-Fluorophenyl)thio)-4-chloropyrimidin-2-amine; 4-Chloro-6-(4-fluorophenylsulfanyl)pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-[(4-Fluorophenyl)Sulfanyl]-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.