Description

2-[(2-Amino-5-Chloro-6-Methyl-4-Pyrimidinyl)Sulfanyl]Acetic Acid is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for further chemical modification. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs where this pyrimidine-thioacetic acid structure is integral.
• Bioconjugation & Probe Development: The reactive thioacetic acid group allows for potential use in creating biochemical probes or conjugates for diagnostic applications.

Basic Information

Product Name	2-[(2-Amino-5-Chloro-6-Methyl-4-Pyrimidinyl)Sulfanyl]Acetic Acid
CAS No.	338976-58-2
Molecular Formula	C7H8ClN3O2S
Molecular Weight	233.67 g/mol
Synonyms	2-[(2-Amino-5-chloro-6-methyl-4-pyrimidinyl)thio]acetic acid; (2-Amino-5-chloro-6-methylpyrimidin-4-yl)sulfanylacetic acid; 4-Pyrimidineacetic acid, 2-amino-5-chloro-6-methyl-4-(thioxo-λ⁴-sulfanylidene)-; Acetic acid, 2-[(2-amino-5-chloro-6-methyl-4-pyrimidinyl)thio]-; 338976-58-2; 2-Amino-5-chloro-6-methyl-4-pyrimidinylthioacetic acid
EINECS	Contact for details

Quality Control

Our production of 2-[(2-Amino-5-Chloro-6-Methyl-4-Pyrimidinyl)Sulfanyl]Acetic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.