Description

4-(6-([(4-Chlorophenyl)Sulfonyl]Methyl)-2-Methyl-4-Pyrimidinyl)Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidinyl-morpholine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Biochemical Reagent: Acts as a reference standard or a tool compound in biochemical and pharmacological assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce complex sulfonyl and heterocyclic functionalities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-(6-([(4-Chlorophenyl)Sulfonyl]Methyl)-2-Methyl-4-Pyrimidinyl)Morpholine
CAS No.	338960-59-1
Molecular Formula	C16H18ClN3O3S
Molecular Weight	367.85 g/mol
Synonyms	4-[6-[(4-Chlorophenyl)sulfonylmethyl]-2-methylpyrimidin-4-yl]morpholine; 4-(6-{[(4-Chlorophenyl)sulfonyl]methyl}-2-methyl-4-pyrimidinyl)morpholine; 4-(6-((4-Chlorophenyl)sulfonyl)methyl)-2-methylpyrimidin-4-yl)morpholine; Morpholine, 4-[6-[[(4-chlorophenyl)sulfonyl]methyl]-2-methyl-4-pyrimidinyl]-; 338960-59-1; 4-(6-((4-Chlorobenzene)sulfonyl)methyl)-2-methylpyrimidin-4-yl)morpholine
EINECS	Contact for details

Quality Control

Our production of 4-(6-([(4-Chlorophenyl)Sulfonyl]Methyl)-2-Methyl-4-Pyrimidinyl)Morpholine adheres to stringent quality management systems. Each batch is rigorously tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical quality guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.