Description

Ethyl 2-((5-Methoxy-4-[3-(Trifluoromethyl)Phenoxy]-2-Pyrimidinyl)Sulfanyl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine and trifluoromethylphenoxy structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis: Serves as a versatile synthon in organic chemistry for constructing complex molecules containing pyrimidine and aryl ether functionalities.
• Material Science Precursor: Potential use in the development of specialty chemicals and advanced materials with specific electronic or photophysical properties.

Basic Information

Product Name	Ethyl 2-((5-Methoxy-4-[3-(Trifluoromethyl)Phenoxy]-2-Pyrimidinyl)Sulfanyl)Acetate
CAS No.	338423-35-1
Molecular Formula	C₁₆H₁₅F₃N₂O₄S
Molecular Weight	388.36 g/mol
Synonyms	Ethyl [5-Methoxy-4-(3-trifluoromethylphenoxy)pyrimidin-2-yl]thioacetate; 2-[(5-Methoxy-4-{[3-(trifluoromethyl)phenyl]oxy}-2-pyrimidinyl)thio]acetic Acid Ethyl Ester; Ethyl (5-Methoxy-4-(3-(trifluoromethyl)phenoxy)pyrimidin-2-yl)thioacetate; CAS 338423-35-1; 338423-35-1; Ethyl 2-((5-Methoxy-4-(3-(trifluoromethyl)phenoxy)pyrimidin-2-yl)thio)acetate; Ethyl 2-((5-Methoxy-4-(α,α,α-trifluoro-m-tolyloxy)-2-pyrimidinyl)thio)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-((5-Methoxy-4-[3-(Trifluoromethyl)Phenoxy]-2-Pyrimidinyl)Sulfanyl)Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.