Description

2-[(4-Chlorobenzyl)Sulfanyl]-5-Methoxy-4-Pyrimidinyl 3-(Trifluoromethyl)Phenyl Ether is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active molecules. Its unique molecular architecture, featuring a pyrimidine core with chlorobenzyl and trifluoromethylphenyl ether substituents, makes it a critical building block for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable pyrimidine scaffold.
• Agrochemical Development: Serves as a building block for creating new active ingredients in herbicides and fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	2-[(4-Chlorobenzyl)Sulfanyl]-5-Methoxy-4-Pyrimidinyl 3-(Trifluoromethyl)Phenyl Ether
CAS No.	338423-07-7
Molecular Formula	C19H14ClF3N2O2S
Molecular Weight	426.84 g/mol
Synonyms	5-Methoxy-2-[(4-chlorophenyl)methyl]sulfanyl-4-[3-(trifluoromethyl)phenoxy]pyrimidine; 4-[3-(Trifluoromethyl)phenoxy]-2-[[(4-chlorophenyl)methyl]thio]-5-methoxypyrimidine; 2-((4-Chlorobenzyl)thio)-5-methoxy-4-(3-(trifluoromethyl)phenoxy)pyrimidine; CAS 338423-07-7; 4-(3-Trifluoromethylphenoxy)-2-[(4-chlorobenzyl)thio]-5-methoxypyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Chlorobenzyl)Sulfanyl]-5-Methoxy-4-Pyrimidinyl 3-(Trifluoromethyl)Phenyl Ether is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our products are suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.