Description

4-(2-Phenyl-1,3-thiazol-5-yl)-2-pyrimidinamine is a high-purity heterocyclic organic compound featuring a fused thiazole-pyrimidine core structure, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Chemical Research & Development: Used as a versatile scaffold for constructing complex heterocyclic libraries in medicinal chemistry.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor-ligand interactions due to its privileged structure.
• Agrochemical Development: Investigated as an intermediate for novel crop protection agents and pesticides.
• Material Science: Explored as a potential monomer or additive for specialty polymers and advanced organic materials.

Basic Information

Product Name	4-(2-Phenyl-1,3-thiazol-5-yl)-2-pyrimidinamine
CAS No.	338414-61-2
Molecular Formula	C13H10N4S
Molecular Weight	254.31 g/mol
Synonyms	2-Amino-4-(2-phenyl-1,3-thiazol-5-yl)pyrimidine; 5-(2-Aminopyrimidin-4-yl)-2-phenyl-1,3-thiazole; 4-(2-Phenylthiazol-5-yl)pyrimidin-2-amine; 338414-61-2; 4-(2-Phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-(2-phenyl-1,3-thiazol-5-yl)-; 4-(2-Phenyl-1,3-thiazol-5-yl)-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 4-(2-Phenyl-1,3-thiazol-5-yl)-2-pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.